Vector and Cellular Facility

MetroHealth is the first safety-net hospital in the United States to offer in-house viral vector production. 

Questions: [email protected]  |  Request a Viral Vector

Vector and Cellular Facility

MetroHealth is the first safety-net hospital in the United States to offer in-house viral vector production. 

Questions: [email protected]  |  Request a Viral Vector

State-of-the-Art Vector and Cellular Facility

The MetroHealth System’s state-of-the-art Vector and Cellular Facility enables:

  • Quick, reliable plasmid production
  • Viral vector creation
  • Development of chimeric antigen receptor T-cell (CAR-T) therapy and other cellular products

Jino Park, PhD working in the lab with Vector Lab staff

Vector and Cellular Facility Features

Staffed by trained researchers and oncologists and led by prominent MetroHealth leaders, the vector and cellular facility offers an FDA Good Manufacturing Practice (GMP)-compliant clean lab, as well as supportive production and storage spaces. 

This includes:

  • 3 ISO Class 7 production suites with ISO Class 8 support areas, plasmid production, and QC/OC areas
  • Unidirectional flow of personnel and materials for multi-suite labs
  • Integrated 24/7 Automated Particle Measuring System
  • Integrated 24/7 Automated Essential Equipment Monitoring System 
  • Uninterrupted power supply and emergency power systems
  • Independent CO2 and N2 gas supply with automated backup
  • Dual Independent HVAC system with redundant fan design
  • Independent Controlled Access System
  • In-house Testing for Comprehensive Quality Control 

 

William Tse, MD in hallway with arms crossed

“When it comes to the production of investigational therapies, viral vectors are often produced in commercial facilities, which can involve high costs and long wait times.

By integrating all elements of cellular therapy development in one location, we will be able to speed up production for investigational cellular therapies, accelerating clinical research.”

William W. Tse, MD, FACP, MBA 

Blue envelope with @ symbol
Interested in Producing Viral Vector?

We look forward to partnering with the academic and biotech community to produce viral vector for investigational therapies to expedite clinical research. 

For more information, please contact us at [email protected].

Meet Our Leaders
William W. Tse, MD
William W. Tse, MD, FACP, MBA
Director of Hematology and Oncology Division, The MetroHealth System
Meet Dr. Tse
Portrait photo of Jino park, PhD
Jino Park, PhD, MS
Director, Center for Advanced Cellular Immunotherapy, The MetroHealth System
Meet Dr. Park
William W. Tse, MD
William W. Tse, MD, FACP, MBA
Director of Hematology and Oncology Division, The MetroHealth System Meet Dr. Tse
Portrait photo of Jino park, PhD
Jino Park, PhD, MS
Director, Center for Advanced Cellular Immunotherapy, The MetroHealth System Meet Dr. Park
MetroHealth Logo