Core Facilities
The MetroHealth Research Institute is assigned over 70,000 square feet of space across the System.
The vast majority of the assigned space is in the Rammelkamp Center for Education and Research. This building houses a variety of research programs and all of the programs that require wet-laboratory space. A number of core services and equipment are provided in support of the basic research groups.
These include the following:
Live Cell Imaging
- Leica Microsystem SP8 Confocal Imaging System live cell imaging. Equipped with white light laser, 405 diode, argon laser. Resonant scanner for fast live cell imaging.
- Leica Thunder Imager 3D Assay System for live cell/organoids or slides with automatic blur removal. Avia AI Analysis system also available for processing of data.
- Leica wide-field inverted microscope with Hamamatsu camera and Metamorph software.
- Molecular Devices Image Express Spinning Disk confocal for high-thruput organoid studies.
- PIE-FCCS Microscope
Imaging of Slides
- Leica Microsystem SPE Confocal Imaging system with 405, 532, 635 lasers.
Flow Cytometry
- Beckman Cytoflex equipped with 3 lasers and 13 filters.
Cell Sorter
- Sony MA 900 equipped with 4 lasers and 14 parameters.
Particle Analysis
- ZetaView PMX-230-Z-488/640-Twin Laser System, with fixed cell assembly.
Other
- Perkin Elmer Victor Nivo multiplate reader for assays
- Spectrophotometer
- Huygens Deconvolution and Colocalization analyzer for 3D imaging data acquired from Leica SPE and SP8 Confocal Systems
- Centrifuges
- Leica CM1850 cryostats
- Microtome
- RMC MTX ultramicrotome
Contact Us
Pat Glazebrook, BS
Research Associate
[email protected]
216-778-8958
Case Western Reserve University School of Medicine Core Facilities
The faculty members at the Center also have the academic affiliation with Case Western Reserve University School of Medicine and have the full access to over 40 service centers and core facilities.
