Jayme Knutson, PhD

Dr. Jayme Knutson

The MetroHealth System

  • Director of Research, Department of Physical Medicine and Rehabilitation
  • Senior Staff Scientist, Department of Physical Medicine and Rehabilitation

Case Western Reserve University

  • Professor, Department of Physical Medicine and Rehabilitation

Louis Stokes Cleveland Veterans Affairs Medical Center

  • Biomedical Engineer, Research Service

Cleveland FES Center

  • Associate Director of Movement Restoration


Broad Research Programs

  • Paralysis After Stroke
  • Innovative Rehabilitation Technologies



Dr. Knutson is a tenured Professor in the Department of Physical Medicine and Rehabilitation (PM&R) at the MetroHealth System and Case Western Reserve University (CWRU) School of Medicine. His research focuses on the development, testing, and clinical translation of neurostimulation therapies for upper limb paresis after stroke. Dr. Knutson earned his PhD in biomedical engineering from CWRU in 2004 and received additional training as a Clinical Research Scholar with the Case/Cleveland Clinic Multidisciplinary Clinical Research Training Program (NIH K12/KL2) from 2005 to 2009.

He is a co-inventor of Contralaterally Controlled Functional Electrical Stimulation (CCFES), a patented neuromuscular electrical stimulation therapy for rehabilitation of individuals with hemiparesis due to stroke or cerebral palsy. Dr. Knutson’s research has been supported by grants from the National Institutes of Health and the Department of Veterans Affairs. He has been the principal investigator on clinical trials investigating the efficacy of CCFES and other functional electrical stimulation interventions to improve upper and lower limb function in stroke patients.

He has also served as a site PI and as a Co-Investigator on many clinical trials. He leads an interdisciplinary team of physical and occupational therapists, physiatrists, engineers, and neuroscientists. As the Director of Research at MetroHealth Rehabilitation Institute, Dr. Knutson coordinates research efforts and resources for investigators and research education for the MetroHealth PM&R Residency program.



National Library of Medicine bibliography page


Professional Society Memberships

    2013-present    American Congress of Rehabilitation Medicine 
    2018-present    International Society of Physical and Rehabilitation Medicine


Specific Research Topics


Contact Information

MetroHealth Old Brooklyn Health Center
4229 Pearl Road, Rm SM1-057
Cleveland OH, 44109
Phone: 216-957-3557
Email: [email protected]; [email protected]