PubMed Publications

• Pulse Pressure and Adverse Maternal and Perinatal Outcomes in Patients With Mild Chronic Hypertension During Pregnancy Abstract: CONCLUSION: Increasing pulse pressure was modestly associated with an adverse composite, specifically preeclampsia with severe features and indicated PTB before 35 weeks of gestation, but it was negatively associated with SGA birth weight less than the 5th percentile. The role of antepartum pulse pressure in reducing adverse pregnancy outcomes in patients with chronic hypertension should be further investigated.
• Long COVID After Acquisition of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) During Pregnancy Compared With Outside of Pregnancy Abstract: CONCLUSION: Acquisition of SARS-CoV-2 during pregnancy was not associated with a differential risk of long COVID at 6 months compared with similar-aged individuals who acquired SARS-CoV-2 outside of pregnancy.
• Olfactory Dysfunction After SARS-CoV-2 Infection in the RECOVER Adult Cohort Abstract: CONCLUSIONS AND RELEVANCE: In this cohort study of RECOVER-Adult participants, self-reported change or loss in smell or taste was an accurate signal of verified hyposmia, but a high rate of hyposmia among those with no reported change or loss was also observed. Formal smell testing may be considered in those with prior SARS-CoV-2 infection to diagnose occult hyposmia and counsel patients about risks.
• Application of Generative AI to Enhance Obstetrics and Gynecology Research Abstract: The rapid evolution of large-language models such as ChatGPT, Claude, and Gemini is reshaping the methodological landscape of obstetrics and gynecology (OBGYN) research. This narrative review provides a comprehensive account of generative AI capabilities, key use cases, and recommended safeguards for investigators. First, generative AI expedites hypothesis generation, enabling researchers to interrogate vast corpora and surface plausible, overlooked questions. Second, it streamlines systematic...
• Considerations for obstetric management of births 22-25 weeks' gestation Abstract: Preterm birth between 22 and 25 5/7 weeks complicates <1% of live births within the United States though contributes more than 20% of infant mortality within the first year of life. Ante- and intrapartum interventions such as antenatal corticosteroids, magnesium sulfate, and tocolytic and antibiotic therapies have been shown effective in optimizing postnatal prognosis in births at 24 weeks and beyond. Interventions, mode of delivery, and resuscitation plans should ideally be discussed with the...
• A Multidisciplinary Standardized Patient Simulation for Using Trauma-Informed Care for Pregnant Patients Abstract: INTRODUCTION: Pregnant patients with prior traumatic experiences and their providers face challenges during prenatal care, peripartum, and postpartum. To date, no structured simulations have been published focused on improving care for patients in subsequent pregnancies.
• Intrapartum and 30-Day Postpartum Complications in Patients With Antenatal COVID-19 Infection: A Retrospective Cohort Study Abstract: Objective: The study was aimed at comparing intrapartum and postpartum outcomes between pregnant patients with and without antenatal COVID-19 infection using aggregated, deidentified electronic health record (EHR) data. Design and Setting: This retrospective cohort study included data from over 80 health care organizations within the TriNetX Analytics Research Network. Population: Individuals admitted for delivery from Jan 2020 to May 2023 were studied. Methods: We studied individuals with...
• Autoimmune Condition Diagnosis Following Recurrent Pregnancy Loss Abstract: CONCLUSIONS: Using a large research database of patients with RPL, we were able to demonstrate that an antecedent diagnosis of RPL is associated with increased risk of subsequent diagnosis of an AIC, often between 1 and 10 years after RPL.
• Antihypertensive therapy and unplanned maternal postpartum healthcare utilization in patients with mild chronic hypertension Abstract: CONCLUSION: While treatment of mild CHTN during pregnancy and postpartum was not significantly associated with overall unplanned healthcare resource utilization, it was associated with lower rates of postpartum ED and triage visits.
• Measurement of circulating viral antigens post-SARS-CoV-2 infection in a multicohort study Abstract: OBJECTIVES: To determine the proportion of individuals with detectable antigen in plasma or serum after SARS-CoV-2 infection and the association of antigen detection with postacute sequelae of COVID-19 (PASC) symptoms.
• Blood pressure control in pregnant patients with chronic hypertension and diabetes: should &lt;130/80 be the target? Abstract: CONCLUSION: In those with chronic hypertension and diabetes prior to 20 weeks, achieving an average goal blood pressure of <130/80 mm Hg may be associated with improved perinatal outcomes.
• Severe Hypertension in Pregnancy: Progress Made and Future Directions for Patient Safety, Quality Improvement, and Implementation of a Patient Safety Bundle Abstract: Hypertensive disorders of pregnancy account for approximately 5% of pregnancy-related deaths in the United States and are one of the leading causes of maternal morbidity. Focus on improving patient outcomes in the setting of hypertensive disorders of pregnancy has increased in recent years, and quality improvement initiatives have been implemented across the United States. This paper discusses patient safety and quality initiatives for hypertensive disorders of pregnancy, with an emphasis on...
• Effects of Antihypertensive Therapy During Pregnancy on Postpartum Blood Pressure Control Abstract: CONCLUSION: Antihypertensive treatment of mild chronic hypertension during pregnancy was associated with better BP control below 140/90 mm Hg in the immediate postpartum period.
• Differentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort Abstract: CONCLUSION: Overall, no evidence was found that any of the 25 routine clinical laboratory values assessed in this study could serve as a clinically useful biomarker of PASC.
• Four Important Questions About Between-Hospital Differences in Care at &lt;25 Weeks' Gestation Abstract: No abstract